This document summarizes observations of the W49 giant molecular cloud (GMC) using the PMO 14m telescope and the Submillimeter Array (SMA). The PMO observations mapped the entire GMC in various molecular lines at scales up to 113 pc, while the SMA mosaic mapped the central star-forming region W49N at scales down to 0.5 pc. The observations are used to derive the mass structure of the GMC across all scales. The main findings are that the W49 GMC has a total gas mass of 1.1 million solar masses within 60 pc and 2x10^5 solar masses within 6 pc. The mass is distributed in a hierarchical network of filaments converging toward the central