The document discusses the role of the science of networks in enhancing understanding and optimization of social networks, particularly in the context of Web 2.0 and cyberinfrastructure. It emphasizes the development of tools and algorithms for analyzing and improving social networking for multidisciplinary collaboration while exploring the social drivers for creating and sustaining these networks. Additionally, it introduces the ci-know system as a suite of software tools aimed at enhancing knowledge sharing and resource location within a networked environment.